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Recombinant human LYRM1 protein

Cat:P03131

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-122aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: LYRM1
【Full Name】: LYR motif containing 1
【Uniprot】: O43325
【Gene ID】: 57149
【Species Reactivity】: Human Mouse Rat (Zebrafish)
【Mol Mass】: 14kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins.Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus.This gene is widely expressed with high levels in omental adipose tissue of obese individuals.In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis.Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction.Alternative splicing results in multiple transcript variants.

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