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Recombinant human PGD protein

Cat:P03141

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-350aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: PGD
【Full Name】: phosphogluconate dehydrogenase
【Uniprot】: P52209
【Gene ID】: 5226
【Species Reactivity】: Human Mouse Rat (Fruit fly Sheep Pig A.thaliana)
【Mol Mass】: 38kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt.Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant.Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.Several transcript variants encoding different isoforms have been found for this gene.

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