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Recombinant human COX16 protein

Cat:P03150

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-106aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: COX16
【Full Name】: COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
【Uniprot】: Q9P0S2
【Gene ID】: 51241
【Species Reactivity】: Human Mouse (Bovine Gorilla)
【Mol Mass】: 12kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2) .Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6.Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.

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