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Recombinant human UBE2V1 protein

Cat：P03153

Summary:

【Derived From】： E.coli

【Endotoxin】： Not measured

【Amino Acid】： 1-147aa

【Purity】： ≥85% by SDS-PAGE.

【Name】： UBE2V1

【Full Name】： ubiquitin-conjugating enzyme E2 variant 1

【Uniprot】： Q13404

【Gene ID】： 7335

【Species Reactivity】： Human Mouse (Bovine Chicken Gorilla)

【Mol Mass】： 16kDa

【Application】： Immunology research

【Purification】： NI-NTA affinity purification

【Bioactive】： No activity experimental data, to be verified.

【Tag】： With a 6×His tag at the N/C-terminus.

【Concentration】： 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.)

【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year.

【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family.They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s.The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene.It is thought to be involved in the control of differentiation by altering cell cycle behavior.Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified.Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

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