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Recombinant human SOX30 protein

Cat:P03176

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-350aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: SOX30
【Full Name】: SRY (sex determining region Y)-box 30
【Uniprot】: O94993
【Gene ID】: 11063
【Species Reactivity】: Human Mouse (Zebrafish)
【Mol Mass】: 38kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate.The encoded protein acts as a transcriptional regulator when present in a complex with other proteins.It can activate p53 transcription to promote tumor cell apoptosis in lung cancer.The protein may be involved in the differentiation of developing male germ cells.Alternative splicing of this gene results in multiple transcript variants.A related pseudogene has been identified on chromosome 5.

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