Summary:
Recombinant human GTF3C6 protein
Cat：P03178
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-213aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： GTF3C6 |
| 【Full Name】： general transcription factor IIIC，polypeptide 6，alpha 35kDa |
| 【Uniprot】： Q969F1 |
| 【Gene ID】： 112495 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 24kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs).GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase.GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin
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