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Recombinant human HNRNPA2B1 protein

Cat:P03183

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-249aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: HNRNPA2B1
【Full Name】: heterogeneous nuclear ribonucleoprotein A2/B1
【Uniprot】: I6L957
【Gene ID】: 3181
【Species Reactivity】: Human Mouse Rat (Bovine Gorilla)
【Mol Mass】: 28kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA).These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport.While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm.The hnRNP proteins have distinct nucleic acid binding properties.The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs.This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms.

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