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Recombinant human FUNDC2 protein

Cat：P03194

Summary:

【Derived From】： E.coli

【Endotoxin】： Not measured

【Amino Acid】： 1-189aa

【Purity】： ≥85% by SDS-PAGE.

【Name】： FUNDC2

【Full Name】： FUN14 domain containing 2

【Uniprot】： Q9BWH2

【Gene ID】： 65991

【Species Reactivity】： Human Mouse (Pig Bovine)

【Mol Mass】： 21kDa

【Application】： Immunology research

【Purification】： NI-NTA affinity purification

【Bioactive】： N0

【Tag】： With a 6×His tag at the N/C-terminus.

【Concentration】： 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)

【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year.

【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

FUNDC2 (FUN14 domain-containing protein 2), also known as HCC-3 (cervical cancer proto-oncogene 3 protein), HCBP6 (hepatitis C virus core-binding protein 6) or DC44, is a 189 amino acid protein belonging to the FUN14 family.The gene encoding FUNDC2 maps to human chromosome Xq28.The X and Y chromosomes are the human sex chromosomes.Chromosome X consists of about 153 million base pairs and nearly 1,000 genes.The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development.More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome.A single copy of X alone leads to Turner's syndrome.More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome.Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

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