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Recombinant human MTAP protein

Cat:P03223

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-283aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: MTAP
【Full Name】: methylthioadenosine phosphorylase
【Uniprot】: Q13126
【Gene ID】: 4507
【Species Reactivity】: Human Mouse Rat (Zebrafish Fruit fly Bovine)
【Mol Mass】: 31kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine.The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted.Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.

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