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Recombinant human SFRS5 protein

Cat:P03229

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-272aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: SFRS5
【Full Name】: splicing factor,arginine/serine-rich 5
【Uniprot】: Q13243
【Gene ID】: 6430
【Species Reactivity】: Human Mouse Rat
【Mol Mass】: 31kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome.Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins.The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors.In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation.Alternative splicing results in multiple transcript variants.

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