Summary:
Recombinant human DMC1 protein
Cat：P03231
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-340aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： DMC1 |
| 【Full Name】： DMC1 dosage suppressor of mck1 homolog，meiosis-specific homologous recombination (yeast) |
| 【Uniprot】： Q14565 |
| 【Gene ID】： 11144 |
| 【Species Reactivity】： Human Mouse (A.thaliana) |
| 【Mol Mass】： 38kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins).Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis.This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information.Alternative splicing results in multiple transcript variants.
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