Summary:
Recombinant human PPP1R1A protein
Cat：P03243
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-171aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： PPP1R1A |
| 【Full Name】： protein phosphatase 1，regulatory (inhibitor) subunit 1A |
| 【Uniprot】： Q13522 |
| 【Gene ID】： 5502 |
| 【Species Reactivity】： Human Mouse Rat (Rabbit Dog) |
| 【Mol Mass】： 19kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： No activity experimental data, to be verified. |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Inhibitor of protein-phosphatase 1.This protein may be important in hormonal control of glycogen metabolism.Hormones that elevate intracellular cAMP increase I-1 activity in many tissues.I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA.Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B).Does not inhibit type-2 phosphatases.
Verified picture
