Summary:
Recombinant human OTX2 protein
Cat：P03251
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-289aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： OTX2 |
| 【Full Name】： orthodenticle homeobox 2 |
| 【Uniprot】： P32243 |
| 【Gene ID】： 5015 |
| 【Species Reactivity】： Human Mouse Rat (Zebrafish) |
| 【Mol Mass】： 32kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors.The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development.The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis.Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6).This gene is also suspected of having an oncogenic role in medulloblastoma.Alternative splicing results in multiple transcript variants encoding distinct isoforms.Pseudogenes of this gene are known to exist on chromosomes two and nine.
Verified picture
