Summary:
Recombinant human PTH1R protein
Cat：P03253
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 27-189aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： PTH1R |
| 【Full Name】： parathyroid hormone 1 receptor |
| 【Uniprot】： Q03431 |
| 【Gene ID】： 5745 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Dog Pig Gorilla) |
| 【Mol Mass】： 17kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene is a member of the G-protein coupled receptor family 2.This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH).The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis.Two transcript variants encoding the same protein have been found for this gene
Verified picture
