Summary:
Recombinant human CD1D protein
Cat：P03260
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 20-316aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： CD1D |
| 【Full Name】： CD1d molecule |
| 【Uniprot】： P15813 |
| 【Gene ID】： 912 |
| 【Species Reactivity】： Human Mouse Rat (Gorilla Sheep) |
| 【Mol Mass】： 38kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.The human genome contains five CD1 family genes organized in a cluster on chromosome 1.The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands.The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.Two transcript variants encoding different isoforms have been found for this gene.
Verified picture
