Summary:
Recombinant human PRMT2 protein
Cat：P03268
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 84-433aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： PRMT2 |
| 【Full Name】： protein arginine methyltransferase 2 |
| 【Uniprot】： P55345 |
| 【Gene ID】： 3275 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 39kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4.Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation.Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation.Enhances PGR, PPARG, RARA-mediated transactivation.May inhibit NF-kappa-B transcription and promote apoptosis.Represses E2F1 transcriptional activity (in a RB1-dependent manner).May be involved in growth regulation.
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