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Recombinant human ICK protein

Cat:P03269

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-293aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: ICK
【Full Name】: intestinal cell (MAK-like) kinase
【Uniprot】: Q9UPZ9
【Gene ID】: 22858
【Species Reactivity】: Human Mouse Rat (A.thaliana)
【Mol Mass】: 34kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases.This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases.The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation.Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

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