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Recombinant human OSBPL2 protein

Cat：P03277

Summary:

【Derived From】： E.coli

【Endotoxin】： Not measured

【Amino Acid】： 132-481aa

【Purity】： ≥85% by SDS-PAGE.

【Name】： OSBPL2

【Full Name】： oxysterol binding protein-like 2

【Uniprot】： Q9H1P3

【Gene ID】： 9885

【Species Reactivity】： Human Mouse

【Mol Mass】： 38kDa

【Application】： Immunology research

【Purification】： NI-NTA affinity purification

【Bioactive】： N0

【Tag】： With a 6×His tag at the N/C-terminus.

【Concentration】： 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)

【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year.

【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors.Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain.In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol.The protein associates with the Golgi apparatus.Transcript variants encoding different isoforms have been described.

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