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Recombinant human CDCA4 protein

Cat:P03279

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-241aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: CDCA4
【Full Name】: cell division cycle associated 4
【Uniprot】: Q9BXL8
【Gene ID】: 55038
【Species Reactivity】: Human Mouse
【Mol Mass】: 26kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a protein that belongs to the E2F family of transcription factors.This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway.It also functions in the regulation of JUN oncogene expression.This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis.Two alternatively spliced transcript variants encoding the same protein have been noted for this gene.Two pseudogenes have also been identified on chromosome 1.

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