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Recombinant human LDB1 protein

Cat:P03301

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-411aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: LDB1
【Full Name】: LIM domain binding 1
【Uniprot】: Q86U70
【Gene ID】: 8861
【Species Reactivity】: Human Mouse (Chicken Zebrafish)
【Mol Mass】: 47kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors.May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions.Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1.Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression.Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity).

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