Summary:
Recombinant human SUMF2 protein
Cat：P03309
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-301aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： SUMF2 |
| 【Full Name】： sulfatase modifying factor 2 |
| 【Uniprot】： Q8NBJ7 |
| 【Gene ID】： 25870 |
| 【Species Reactivity】： Human Mouse (Bovine Gorilla) |
| 【Mol Mass】： 34kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly).The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity.The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum.This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity.Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Verified picture
