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Recombinant human RAC2 protein

Cat:P03314

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-192aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: RAC2
【Full Name】: ras-related C3 botulinum toxin substrate 2 (rho family,small GTP binding protein Rac2)
【Uniprot】: P15153
【Gene ID】: 5880
【Species Reactivity】: Human Mouse (Bovine Pig Fruit fly A.thaliana)
【Mol Mass】: 21kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins.The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization.Activity of this protein is also involved in the generation of reactive oxygen species.Mutations in this gene are associated with neutrophil immunodeficiency syndrome.There is a pseudogene for this gene on chromosome 6.

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