Summary:
Recombinant human HMGB2 protein
Cat：P03319
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-209aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： HMGB2 |
| 【Full Name】： high-mobility group box 2 |
| 【Uniprot】： P26583 |
| 【Gene ID】： 3148 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Chicken Pig A.thaliana) |
| 【Mol Mass】： 24kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the non-histone chromosomal high mobility group protein family.The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells.In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles.These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility.This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
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