Summary:
Recombinant human NMNAT1 protein
Cat：P03325
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-279aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： NMNAT1 |
| 【Full Name】： nicotinamide nucleotide adenylyltransferase 1 |
| 【Uniprot】： Q9HAN9 |
| 【Gene ID】： 64802 |
| 【Species Reactivity】： Human Mouse (Bovine) |
| 【Mol Mass】： 32kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD).The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus.Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons.Mutations in this gene have been associated with Leber congenital amaurosis 9.Alternative splicing results in multiple transcript variants.Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15.
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