Summary:
Recombinant human CCDC67 protein
Cat：P03326
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-341aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： CCDC67 |
| 【Full Name】： coiled-coil domain containing 67 |
| 【Uniprot】： Q05D60 |
| 【Gene ID】： 159989 |
| 【Species Reactivity】： Human Mouse Rat |
| 【Mol Mass】： 38kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells.Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles.Probably sufficient for the specification and formation of the deuterosome inner core.Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity).
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