Summary:
Recombinant human THAP6 protein
Cat：P03328
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-222aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： THAP6 |
| 【Full Name】： THAP domain containing 6 |
| 【Uniprot】： Q8TBB0 |
| 【Gene ID】： 152815 |
| 【Species Reactivity】： Human |
| 【Mol Mass】： 26kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
THAP6 (THAP domain-containing protein 6) is a 222 amino acid protein that contains one THAP-type zinc finger and exists as two alternatively spliced isoforms.The gene that encodes THAP6 consists of approximately 36,528 bases and maps to human chromosome 4q21.1.Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes.Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is encoded by a gene that maps to chromosome 4.FGFR-3 is also encoded by a gene located on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer.Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
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