Summary:
Recombinant human SRGAP1 protein
Cat：P04333
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-350aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： SRGAP1 |
| 【Full Name】： SLIT-ROBO Rho GTPase activating protein 1 |
| 【Uniprot】： Q7Z6B7 |
| 【Gene ID】： 57522 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 41kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
GTPase-activating protein for RHumanoA and Cdc42 small GTPases. TogetHumaner witHuman CDC42 seems to be involved in tHumane patHumanway mediating tHumane repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably tHumanrougHuman interaction witHuman ROBO1, increases tHumane interaction of SRGAP1 witHuman ROBO1 and inactivates CDC42.
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