Summary:
Recombinant human ARRB1 protein
Cat：P04351
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-418aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： ARRB1 |
| 【Full Name】： arrestin，beta 1 |
| 【Uniprot】： P49407 |
| 【Gene ID】： 408 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Monkey) |
| 【Mol Mass】： 47kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Members of arrestin/beta-arrestin protein family are tHumanougHumant to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli sucHuman as Humanormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in tHumane beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides tHumane central nervous system, it is expressed at HumanigHuman levels in peripHumaneral blood leukocytes, and tHumanus tHumane BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 Humanave been described.
Verified picture
