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Recombinant human SLC4A4 protein

Cat:P05322

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-348aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: SLC4A4
【Full Name】: solute carrier family 4,sodium bicarbonate cotransporter,member 4
【Uniprot】: Q9Y6R1
【Gene ID】: 8671
【Species Reactivity】: Human Mouse Rat (Bovine Pig Rabbit)
【Mol Mass】: 39kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene.

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