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Recombinant human KCNN3 protein

Cat:P05377

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 240-425aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: KCNN3
【Full Name】: potassium intermediate/small conductance calcium-activated channel,subfamily N,member 3
【Uniprot】: Q9UGI6
【Gene ID】: 3782
【Species Reactivity】: Human Mouse Rat (Pig)
【Mol Mass】: 21kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.

Verified picture