Summary:
Recombinant human MTHFS protein
Cat：P03352
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-203aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： MTHFS |
| 【Full Name】： 5，10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| 【Uniprot】： P49914 |
| 【Gene ID】： 10588 |
| 【Species Reactivity】： Human Mouse (Rabbit) |
| 【Mol Mass】： 23kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism.An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion.Three transcript variants encoding two different isoforms have been found for this gene.
Verified picture
