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Recombinant human SNX6 protein

Cat:P03359

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-291aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: SNX6
【Full Name】: sorting nexin 6
【Uniprot】: Q9UNH7
【Gene ID】: 58533
【Species Reactivity】: Human Mouse (Gorilla)
【Mol Mass】: 32kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the sorting nexin family.Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking.This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor.This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules.Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein.This gene results in two transcripts encoding two distinct isoforms.

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