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Recombinant human DHPS protein

Cat:P03389

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-369aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: DHPS
【Full Name】: deoxyhypusine synthase
【Uniprot】: P49366
【Gene ID】: 1725
【Species Reactivity】: Human Mouse Rat (Bovine A.thaliana)
【Mol Mass】: 41kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A.The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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