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Recombinant human UROD protein

Cat:P03390

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-367aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: UROD
【Full Name】: uroporphyrinogen decarboxylase
【Uniprot】: P06132
【Gene ID】: 7389
【Species Reactivity】: Human Mouse Rat (Fruit fly Sheep Gorilla)
【Mol Mass】: 41kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes an enzyme in the heme biosynthetic pathway.This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains.Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.

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