Summary:
Recombinant human LIPA protein
Cat：P03400
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-321aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： LIPA |
| 【Full Name】： lipase A，lysosomal acid，cholesterol esterase |
| 【Uniprot】： P38571 |
| 【Gene ID】： 3988 |
| 【Species Reactivity】： Human Mouse Rat |
| 【Mol Mass】： 36kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase).This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides.Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease.Alternatively spliced transcript variants have been found for this gene.
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