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Recombinant human RAD51L1 protein

Cat:P03402

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-384aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: RAD51L1
【Full Name】: RAD51-like 1 (S. cerevisiae)
【Uniprot】: O15315
【Gene ID】: 5890
【Species Reactivity】: Human Mouse
【Mol Mass】: 42kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene is a member of the RAD51 protein family.RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination.This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3.Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage.Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

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