Summary:
Recombinant human DDI1 protein
Cat：P03404
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-396aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： DDI1 |
| 【Full Name】： DDI1，DNA-damage inducible 1，homolog 1 (S. cerevisiae) |
| 【Uniprot】： Q8WTU0 |
| 【Gene ID】： 414301 |
| 【Species Reactivity】： Human Mouse Rat (Bovine A.thaliana) |
| 【Mol Mass】： 44kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Probable aspartic protease.Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 .Required, with DDI2, for cellular survival following replication stress.Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity.
Verified picture
