Summary:
Recombinant human AADAT protein
Cat：P03417
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 80-429aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： AADAT |
| 【Full Name】： aminoadipate aminotransferase |
| 【Uniprot】： Q8N5Z0 |
| 【Gene ID】： 51166 |
| 【Species Reactivity】： Human (Bovine Mouse Rat) |
| 【Mol Mass】： 39kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II.The rat protein is a homodimer with two transaminase activities.One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism.The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties.Several transcript variants encoding two different isoforms have been found for this gene.
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