Summary:
Recombinant human RBBP4 protein
Cat：P03433
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-425aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： RBBP4 |
| 【Full Name】： retinoblastoma binding protein 4 |
| 【Uniprot】： Q09028 |
| 【Gene ID】： 5928 |
| 【Species Reactivity】： Human Mouse (Bovine Zebrafish Chicken) |
| 【Mol Mass】： 48kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins.It is present in protein complexes involved in histone acetylation and chromatin assembly.It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation.This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing.It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation.This protein also seems to be involved in transcriptional repression of E2F-responsive genes.Three transcript variants encoding different isoforms have been found for this gene.
Verified picture
