Summary:
Recombinant human ABI2 protein
Cat：P03440
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 127-476aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： ABI2 |
| 【Full Name】： abl interactor 2 |
| 【Uniprot】： Q9NYB9 |
| 【Gene ID】： 10152 |
| 【Species Reactivity】： Human Mouse (A.thaliana) |
| 【Mol Mass】： 38kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2.Part of the WAVE complex that regulates lamellipodia formation.The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.Regulates ABL1/c-Abl-mediated phosphorylation of MENA.As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.
Verified picture
