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Recombinant human H2AFJ protein

Cat:P03455

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-129aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: H2AFJ
【Full Name】: H2A histone family,member J
【Uniprot】: Q9BTM1
【Gene ID】: 55766
【Species Reactivity】: Human
【Mol Mass】: 14kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

TTC38 (tetratricopeptide repeat domain 38) is a 469 amino acid protein that contains three TPR repeats and belongs to the TTC38 family.The gene that encodes TTC38 consists of over 26,000 bases and maps to 22q13.Housing over 500 genes, chromosome 22 is the second smallest chromosome in the human genome.Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.In addition, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

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