Summary:
Recombinant human ARG2 protein
Cat：P03471
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 22-374aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： ARG2 |
| 【Full Name】： arginase，type II |
| 【Uniprot】： P78540 |
| 【Gene ID】： 384 |
| 【Species Reactivity】： Human (Bovine Mouse Rat Rabbit) |
| 【Mol Mass】： 39kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Arginase catalyzes the hydrolysis of arginine to ornithine and urea.At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function.The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney.The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism.Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
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