Summary:
Recombinant human PPP2R1B protein
Cat：P03480
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 318-667aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： PPP2R1B |
| 【Full Name】： protein phosphatase 2 (formerly 2A)，regulatory subunit A，beta isoform |
| 【Uniprot】： P30154 |
| 【Gene ID】： 5519 |
| 【Species Reactivity】： Human Mouse Rat (Pig) |
| 【Mol Mass】： 38kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a constant regulatory subunit of protein phosphatase 2.Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division.It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.This gene encodes a beta isoform of the constant regulatory subunit A.Mutations in this gene have been associated with some lung and colon cancers.Alternatively spliced transcript variants have been described.
Verified picture
