Summary:
Recombinant human TPT1 protein
Cat：P03491
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-172aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： TPT1 |
| 【Full Name】： tumor protein，translationally-controlled 1 |
| 【Uniprot】： P13693 |
| 【Gene ID】： 7178 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Zebrafish Chicken Rabbit Pig A.thaliana) |
| 【Mol Mass】： 20kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： No activity experimental data, to be verified. |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a protein that is a regulator of cellular growth and proliferation.Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions.The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division.It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions.This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells.Alternative splicing results in multiple transcript variants encoding different isoforms.
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