Summary:
Recombinant human SPANXB2 protein
Cat：P03495
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-103aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： SPANXB2 |
| 【Full Name】： SPANX family，member B2 |
| 【Uniprot】： Q9NS25 |
| 【Gene ID】： 100133171 |
| 【Species Reactivity】： Human |
| 【Mol Mass】： 12kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： No activity experimental data, to be verified. |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa.This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X.The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments.This particular family member contains an additional 18 nucleotides in its coding region compared to the other family members in the same gene cluster.This family member is also subject to gene copy number variation.Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa.This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting
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