Summary:
Recombinant human RASSF8 protein
Cat：P03503
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-419aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： RASSF8 |
| 【Full Name】： Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| 【Uniprot】： Q8NHQ8 |
| 【Gene ID】： 11228 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 48kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins.This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration.It is a lung tumor suppressor gene candidate.A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly.Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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