Summary:
Recombinant human STK32A protein
Cat：P03504
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-396aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： STK32A |
| 【Full Name】： serine/threonine kinase 32A |
| 【Uniprot】： Q8WU08 |
| 【Gene ID】： 202374 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 46kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The phosphorylation of proteins by protein kinases and protein phosphatases is a key event in most nuclear and cytoplasmic processes.The ability to activate and deactivate proteins via phosphorylation or dephosphorylation is important for cell division, cell differentiation, DNA repair and transcription.STK32A (serine/threonine kinase 32A), also known as YANK1, is a 396 amino acid protein that belongs to the superfamily of serine/threonine protein kinases and exists as three isoforms.The gene encoding STK32A maps to human chromosome 5, which is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene.Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene.Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome.Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndro
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