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Recombinant human DLX3 protein

Cat：P03509

Summary:

【Derived From】： E.coli

【Endotoxin】： Not measured

【Amino Acid】： 1-287aa

【Purity】： ≥85% by SDS-PAGE.

【Name】： DLX3

【Full Name】： distal-less homeobox 3

【Uniprot】： O60479

【Gene ID】： 1747

【Species Reactivity】： Human Mouse (Zebrafish)

【Mol Mass】： 32kDa

【Application】： Immunology research

【Purification】： NI-NTA affinity purification

【Bioactive】： N0

【Tag】： With a 6×His tag at the N/C-terminus.

【Concentration】： 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)

【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year.

【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes.Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly.The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6.Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation.This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17.Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism.

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