Summary:
Recombinant human GABARAPL2 protein
Cat：P03516
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-117aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： GABARAPL2 |
| 【Full Name】： GABA(A) receptor-associated protein-like 2 |
| 【Uniprot】： P60520 |
| 【Gene ID】： 11345 |
| 【Species Reactivity】： Human (Bovine Mouse Rat) |
| 【Mol Mass】： 14kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Ubiquitin-like modifier involved in intra-Golgi traffic.Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation.It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.Involved in autophagy.Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Verified picture
