Summary:
Recombinant human CHMP2B protein
Cat：P03521
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-213aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： CHMP2B |
| 【Full Name】： chromatin modifying protein 2B |
| 【Uniprot】： Q9UQN3 |
| 【Gene ID】： 25978 |
| 【Species Reactivity】： Human Mouse (Bovine Zebrafish Chicken Gorilla) |
| 【Mol Mass】： 24kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors.ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles.The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes.It is expressed in neurons of all major regions of the brain.Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Verified picture
